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Isothermal chemical denaturation assay for monitoring protein stability and inhibitor interactions
Thermal shift assay (TSA) with altered temperature has been the most widely used method for monitoring protein stability for drug research. However, there is a pressing need for isothermal techniques as alternatives. This urgent demand arises from the limitations of TSA, which can sometimes provide...
Autores principales: | Mahran, Randa, Vello, Niklas, Komulainen, Anita, Malakoutikhah, Morteza, Härmä, Harri, Kopra, Kari |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654576/ https://www.ncbi.nlm.nih.gov/pubmed/37973851 http://dx.doi.org/10.1038/s41598-023-46720-w |
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