Cargando…

High-sensitive spatially resolved T cell receptor sequencing with SPTCR-seq

Spatial resolution of the T cell repertoire is essential for deciphering cancer-associated immune dysfunction. Current spatially resolved transcriptomic technologies are unable to directly annotate T cell receptors (TCR). We present spatially resolved T cell receptor sequencing (SPTCR-seq), which in...

Descripción completa

Detalles Bibliográficos
Autores principales: Benotmane, Jasim Kada, Kueckelhaus, Jan, Will, Paulina, Zhang, Junyi, Ravi, Vidhya M., Joseph, Kevin, Sankowski, Roman, Beck, Jürgen, Lee-Chang, Catalina, Schnell, Oliver, Heiland, Dieter Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654577/
https://www.ncbi.nlm.nih.gov/pubmed/37973846
http://dx.doi.org/10.1038/s41467-023-43201-6