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Effector memory T cells induce innate inflammation by triggering DNA damage and a non-canonical STING pathway in dendritic cells
Cognate interaction between CD4(+) effector memory T (T(EM)) cells and dendritic cells (DCs) induces innate inflammatory cytokine production, resulting in detrimental autoimmune pathology and cytokine storms. While T(EM) cells use tumor necrosis factor (TNF) superfamily ligands to activate DCs, whet...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654673/ https://www.ncbi.nlm.nih.gov/pubmed/37794597 http://dx.doi.org/10.1016/j.celrep.2023.113180 |