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Hemokinin-1 is a mediator of chronic restraint stress-induced pain

The Tac4 gene-derived hemokinin-1 (HK-1) binds to the NK1 receptor, similarly to Substance P, and plays a role in acute stress reactions and pain transmission in mice. Here we investigated Tac4 mRNA expression in stress and pain-related regions and its involvement in chronic restraint stress-evoked...

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Detalles Bibliográficos
Autores principales: Borbély, Éva, Kecskés, Angéla, Kun, József, Kepe, Eszter, Fülöp, Barbara, Kovács-Rozmer, Katalin, Scheich, Bálint, Renner, Éva, Palkovits, Miklós, Helyes, Zsuzsanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654722/
https://www.ncbi.nlm.nih.gov/pubmed/37973885
http://dx.doi.org/10.1038/s41598-023-46402-7