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Reactome pathway analysis from whole-blood transcriptome reveals unique characteristics of systemic sclerosis patients at the preclinical stage

OBJECTIVE: This study aims to characterize differential expressed pathways (DEP) in subjects with preclinical systemic sclerosis (PreSSc) characterized uniquely by Raynaud phenomenon, specific autoantibodies, and/or capillaroscopy positive for scleroderma pattern. METHODS: Whole-blood samples from 3...

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Detalles Bibliográficos
Autores principales: Bellocchi, Chiara, Wang, Xuan, Lyons, Marka A., Marchini, Maurizio, Lorini, Maurizio, Carbonelli, Vincenzo, Montano, Nicola, Assassi, Shervin, Beretta, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654742/
https://www.ncbi.nlm.nih.gov/pubmed/38022564
http://dx.doi.org/10.3389/fimmu.2023.1266391