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Restoring autophagic function: a case for type 2 diabetes mellitus drug repurposing in Parkinson’s disease

Parkinson’s disease (PD) is a predominantly idiopathic pathological condition characterized by protein aggregation phenomena, whose main component is alpha-synuclein. Although the main risk factor is ageing, numerous evidence points to the role of type 2 diabetes mellitus (T2DM) as an etiological fa...

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Detalles Bibliográficos
Autores principales: Greco, Marco, Munir, Anas, Musarò, Debora, Coppola, Chiara, Maffia, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654753/
https://www.ncbi.nlm.nih.gov/pubmed/38027497
http://dx.doi.org/10.3389/fnins.2023.1244022