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A toolbox of astrocyte-specific, serotype-independent adeno-associated viral vectors using microRNA targeting sequences

Astrocytes, one of the most prevalent cell types in the central nervous system (CNS), are critically involved in neural function. Genetically manipulating astrocytes is an essential tool in understanding and affecting their roles. Adeno-associated viruses (AAVs) enable rapid genetic manipulation; ho...

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Detalles Bibliográficos
Autores principales: Gleichman, Amy J., Kawaguchi, Riki, Sofroniew, Michael V., Carmichael, S. Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654773/
https://www.ncbi.nlm.nih.gov/pubmed/37973910
http://dx.doi.org/10.1038/s41467-023-42746-w