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Unconventional structure and mechanisms for membrane interaction and translocation of the NF-κB-targeting toxin AIP56
Bacterial AB toxins are secreted key virulence factors that are internalized by target cells through receptor-mediated endocytosis, translocating their enzymatic domain to the cytosol from endosomes (short-trip) or the endoplasmic reticulum (long-trip). To accomplish this, bacterial AB toxins evolve...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654918/ https://www.ncbi.nlm.nih.gov/pubmed/37973928 http://dx.doi.org/10.1038/s41467-023-43054-z |