Unconventional structure and mechanisms for membrane interaction and translocation of the NF-κB-targeting toxin AIP56

Bacterial AB toxins are secreted key virulence factors that are internalized by target cells through receptor-mediated endocytosis, translocating their enzymatic domain to the cytosol from endosomes (short-trip) or the endoplasmic reticulum (long-trip). To accomplish this, bacterial AB toxins evolve...

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Detalles Bibliográficos
Autores principales: Lisboa, Johnny, Pereira, Cassilda, Pinto, Rute D., Rodrigues, Inês S., Pereira, Liliana M. G., Pinheiro, Bruno, Oliveira, Pedro, Pereira, Pedro José Barbosa, Azevedo, Jorge E., Durand, Dominique, Benz, Roland, do Vale, Ana, dos Santos, Nuno M. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654918/
https://www.ncbi.nlm.nih.gov/pubmed/37973928
http://dx.doi.org/10.1038/s41467-023-43054-z

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