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Short incubation periods of atypical H-type BSE in cattle with EK211 and KK211 prion protein genotypes after intracranial inoculation

In 2006, a case of atypical H-type BSE (H-BSE) was found to be associated with a germline mutation in the PRNP gene that resulted in a lysine substitution for glutamic acid at codon 211 (E211K). The E211K amino acid substitution in cattle is analogous to E200K in humans, which is associated with the...

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Detalles Bibliográficos
Autores principales: Cassmann, Eric D., Frese, Alexis J., Becker, Kelsey A., Greenlee, Justin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655004/
https://www.ncbi.nlm.nih.gov/pubmed/38026617
http://dx.doi.org/10.3389/fvets.2023.1301998