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Erythropoietin suppresses osteoblast apoptosis and ameliorates steroid-induced necrosis of the femoral head in rats by inhibition of STAT1-caspase 3 signaling pathway

BACKGROUND: Steroid-induced avascular necrosis of the femoral head (SANFH) is characterized by osteoblast apoptosis, leading to a loss of bone structure and impaired hip joint function. It has been demonstrated that erythropoietin (EPO) performs a number of biological roles. OBJECTIVE: We examined t...

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Detalles Bibliográficos
Autores principales: Cai, Tingwen, Chen, Siyuan, Wu, Chenghu, Lou, Chao, Wang, Weidan, Lin, Chihao, Jiang, Hongyi, Xu, Xinxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655348/
https://www.ncbi.nlm.nih.gov/pubmed/37978375
http://dx.doi.org/10.1186/s12891-023-07028-y