Molecular and functional profiling of chemotolerant cells unveils nucleoside metabolism-dependent vulnerabilities in medulloblastoma

Chemotherapy resistance is considered one of the main causes of tumor relapse, still challenging researchers for the identification of the molecular mechanisms sustaining its emergence. Here, we setup and characterized chemotherapy-resistant models of Medulloblastoma (MB), one of the most lethal ped...

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Detalles Bibliográficos
Autores principales: Mariotto, Elena, Rampazzo, Elena, Bortolozzi, Roberta, Rruga, Fatlum, Zeni, Ilaria, Manfreda, Lorenzo, Marchioro, Chiara, Canton, Martina, Cani, Alice, Magni, Ruben, Luchini, Alessandra, Bresolin, Silvia, Viola, Giampietro, Persano, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655385/
https://www.ncbi.nlm.nih.gov/pubmed/37978570
http://dx.doi.org/10.1186/s40478-023-01679-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655385/
https://www.ncbi.nlm.nih.gov/pubmed/37978570
http://dx.doi.org/10.1186/s40478-023-01679-7

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