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Interplay of gut microbiota and host epithelial mitochondrial dysfunction is necessary for the development of spontaneous intestinal inflammation in mice

BACKGROUND: Intestinal epithelial cell (IEC) mitochondrial dysfunction involvement in inflammatory bowel diseases (IBD), including Crohn’s disease affecting the small intestine, is emerging in recent studies. As the interface between the self and the gut microbiota, IECs serve as hubs of bidirection...

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Detalles Bibliográficos
Autores principales: Alula, Kibrom M., Dowdell, Alexander S., LeBere, Brittany, Lee, J. Scott, Levens, Cassandra L., Kuhn, Kristine A., Kaipparettu, Benny A., Thompson, Winston E., Blumberg, Richard S., Colgan, Sean P., Theiss, Arianne L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655390/
https://www.ncbi.nlm.nih.gov/pubmed/37978573
http://dx.doi.org/10.1186/s40168-023-01686-9