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Inhibition of Hsp110-STAT3 interaction in endothelial cells alleviates vascular remodeling in hypoxic pulmonary arterial Hypertension model

BACKGROUND: Pulmonary arterial hypertension (PAH) is a progressive and devastating disease characterized by pulmonary vascular remodeling which is associated with the malignant phenotypes of pulmonary vascular cells. Recently, the effects of heat shock protein 110 (Hsp110) in human arterial smooth m...

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Detalles Bibliográficos
Autores principales: Zhao, Congke, Le, Xiangyang, Li, Mengqi, Hu, Yuanbo, Li, Xiaohui, Chen, Zhuo, Hu, Gaoyun, Hu, Liqing, Li, Qianbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655391/
https://www.ncbi.nlm.nih.gov/pubmed/37978368
http://dx.doi.org/10.1186/s12931-023-02600-5