TIGIT reverses IFN-α-promoted Th1-like Tregs via in-sequence effects dependent on STAT4

OBJECTIVES: The induction direction of interferon (IFN)-α in T-cell phenotype and function varies depending on the activation state of the cell and the time of stimulation. To assess the effects of elevated IFN-α on regulatory T cells (Tregs) in systemic lupus erythematosus (SLE) patients, we invest...

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Detalles Bibliográficos
Autores principales: Yu, Shihan, Gu, Jia, Wang, Rui, Lee, Seunghyun, Shan, Yu, Wang, Jiakai, Sun, Yini, Ma, Xiaoxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655484/
https://www.ncbi.nlm.nih.gov/pubmed/37978415
http://dx.doi.org/10.1186/s13075-023-03202-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655484/
https://www.ncbi.nlm.nih.gov/pubmed/37978415
http://dx.doi.org/10.1186/s13075-023-03202-8

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