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TIGIT reverses IFN-α-promoted Th1-like Tregs via in-sequence effects dependent on STAT4
OBJECTIVES: The induction direction of interferon (IFN)-α in T-cell phenotype and function varies depending on the activation state of the cell and the time of stimulation. To assess the effects of elevated IFN-α on regulatory T cells (Tregs) in systemic lupus erythematosus (SLE) patients, we invest...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655484/ https://www.ncbi.nlm.nih.gov/pubmed/37978415 http://dx.doi.org/10.1186/s13075-023-03202-8 |