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Controlling donor and newborn neuron migration and maturation in the eye through microenvironment engineering

Ongoing cell therapy trials have demonstrated the need for precision control of donor cell behavior within the recipient tissue. We present a methodology to guide stem cell–derived and endogenously regenerated neurons by engineering the microenvironment. Being an “approachable part of the brain,” th...

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Detalles Bibliográficos
Autores principales: Soucy, Jonathan R., Todd, Levi, Kriukov, Emil, Phay, Monichan, Malechka, Volha V., Rivera, John Dayron, Reh, Thomas A., Baranov, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655587/
https://www.ncbi.nlm.nih.gov/pubmed/37931105
http://dx.doi.org/10.1073/pnas.2302089120