Multifactorial Remodeling of the Cancer Immunopeptidome by IFNγ

IFNγ alters the immunopeptidome presented on HLA class I (HLA-I), and its activity on cancer cells is known to be important for effective immunotherapy responses. We performed proteomic analyses of untreated and IFNγ-treated colorectal cancer patient-derived organoids and combined this with transcri...

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Detalles Bibliográficos
Autores principales: Newey, Alice, Yu, Lu, Barber, Louise J., Choudhary, Jyoti S., Bassani-Sternberg, Michal, Gerlinger, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655636/
https://www.ncbi.nlm.nih.gov/pubmed/37991387
http://dx.doi.org/10.1158/2767-9764.CRC-23-0121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655636/
https://www.ncbi.nlm.nih.gov/pubmed/37991387
http://dx.doi.org/10.1158/2767-9764.CRC-23-0121

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