Exploring cyclin-dependent kinase inhibitors: a comprehensive study in search of CDK-6 inhibitors using a pharmacophore modelling and dynamics approach

Cancer prevalence and resistance issues in cancer treatment are a significant public health concern globally. Among the existing strategies in cancer therapy, targeting cyclin-dependent kinases (CDKs), especially CDK-6 is found to be one of the most promising targets, as this enzyme plays a pivotal...

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Detalles Bibliográficos
Autores principales: Chagaleti, Bharath Kumar, Saravanan, Venkatesan, Vellapandian, Chitra, Kathiravan, Muthu K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655667/
https://www.ncbi.nlm.nih.gov/pubmed/38019988
http://dx.doi.org/10.1039/d3ra05672d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655667/
https://www.ncbi.nlm.nih.gov/pubmed/38019988
http://dx.doi.org/10.1039/d3ra05672d

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