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Exploring cyclin-dependent kinase inhibitors: a comprehensive study in search of CDK-6 inhibitors using a pharmacophore modelling and dynamics approach
Cancer prevalence and resistance issues in cancer treatment are a significant public health concern globally. Among the existing strategies in cancer therapy, targeting cyclin-dependent kinases (CDKs), especially CDK-6 is found to be one of the most promising targets, as this enzyme plays a pivotal...
Autores principales: | Chagaleti, Bharath Kumar, Saravanan, Venkatesan, Vellapandian, Chitra, Kathiravan, Muthu K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655667/ https://www.ncbi.nlm.nih.gov/pubmed/38019988 http://dx.doi.org/10.1039/d3ra05672d |
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