An induced pluripotent stem cell-based model identifies molecular targets of vincristine neurotoxicity

To model peripheral nerve degeneration and investigate molecular mechanisms of neurodegeneration, we established a cell system of induced pluripotent stem cell (iPSC)-derived sensory neurons exposed to vincristine, a drug that frequently causes chemotherapy-induced peripheral neuropathy. Sensory neu...

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Detalles Bibliográficos
Autores principales: Tsai, Neng-Wei, Lin, Cheng-Chen, Yeh, Ti-Yen, Chiu, Yu-An, Chiu, Hsin-Hui, Huang, Hsiang-Po, Hsieh, Sung-Tsang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655812/
https://www.ncbi.nlm.nih.gov/pubmed/36518084
http://dx.doi.org/10.1242/dmm.049471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655812/
https://www.ncbi.nlm.nih.gov/pubmed/36518084
http://dx.doi.org/10.1242/dmm.049471

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