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iPSCs derived from esophageal atresia patients reveal SOX2 dysregulation at the anterior foregut stage

A series of well-regulated cellular and molecular events result in the compartmentalization of the anterior foregut into the esophagus and trachea. Disruption of the compartmentalization process leads to esophageal atresia/tracheoesophageal fistula (EA/TEF). The cause of EA/TEF remains largely unkno...

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Detalles Bibliográficos
Autores principales: Raad, Suleen, David, Anu, Sagniez, Melanie, Paré, Bastien, Orfi, Zakaria, Dumont, Nicolas A., Smith, Martin A., Faure, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655818/
https://www.ncbi.nlm.nih.gov/pubmed/36317486
http://dx.doi.org/10.1242/dmm.049541