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iPSCs derived from esophageal atresia patients reveal SOX2 dysregulation at the anterior foregut stage
A series of well-regulated cellular and molecular events result in the compartmentalization of the anterior foregut into the esophagus and trachea. Disruption of the compartmentalization process leads to esophageal atresia/tracheoesophageal fistula (EA/TEF). The cause of EA/TEF remains largely unkno...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655818/ https://www.ncbi.nlm.nih.gov/pubmed/36317486 http://dx.doi.org/10.1242/dmm.049541 |