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Bridging condensins mediate compaction of mitotic chromosomes

Eukaryotic chromosomes compact during mitosis into elongated cylinders—and not the spherical globules expected of self-attracting long flexible polymers. This process is mainly driven by condensin-like proteins. Here, we present Brownian-dynamic simulations involving two types of such proteins with...

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Detalles Bibliográficos
Autores principales: Forte, Giada, Boteva, Lora, Conforto, Filippo, Gilbert, Nick, Cook, Peter R., Marenduzzo, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655892/
https://www.ncbi.nlm.nih.gov/pubmed/37976091
http://dx.doi.org/10.1083/jcb.202209113