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Bridging condensins mediate compaction of mitotic chromosomes
Eukaryotic chromosomes compact during mitosis into elongated cylinders—and not the spherical globules expected of self-attracting long flexible polymers. This process is mainly driven by condensin-like proteins. Here, we present Brownian-dynamic simulations involving two types of such proteins with...
Autores principales: | Forte, Giada, Boteva, Lora, Conforto, Filippo, Gilbert, Nick, Cook, Peter R., Marenduzzo, Davide |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655892/ https://www.ncbi.nlm.nih.gov/pubmed/37976091 http://dx.doi.org/10.1083/jcb.202209113 |
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