Pollutants enhance IgE sensitization in the gut via local alteration of vitamin D-metabolizing enzymes

Mechanisms linking ingested pollutants to increased incidence of allergy are poorly understood. We report that mice exposed to low doses of cadmium develop higher IgE responses following oral allergen sensitization and more severe allergic symptoms upon allergen challenge. The environmentally releva...

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Detalles Bibliográficos
Autores principales: Kim, Eunsoo, Bonnegarde-Bernard, Astrid, Opiyo, Stephen O., Joldrichsen, Marisa R., Attia, Zayed, Ahmer, Brian H., Cormet-Boyaka, Estelle, Boyaka, Prosper N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655957/
https://www.ncbi.nlm.nih.gov/pubmed/34504311
http://dx.doi.org/10.1038/s41385-021-00440-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655957/
https://www.ncbi.nlm.nih.gov/pubmed/34504311
http://dx.doi.org/10.1038/s41385-021-00440-4

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