Cargando…
Pollutants enhance IgE sensitization in the gut via local alteration of vitamin D-metabolizing enzymes
Mechanisms linking ingested pollutants to increased incidence of allergy are poorly understood. We report that mice exposed to low doses of cadmium develop higher IgE responses following oral allergen sensitization and more severe allergic symptoms upon allergen challenge. The environmentally releva...
Autores principales: | Kim, Eunsoo, Bonnegarde-Bernard, Astrid, Opiyo, Stephen O., Joldrichsen, Marisa R., Attia, Zayed, Ahmer, Brian H., Cormet-Boyaka, Estelle, Boyaka, Prosper N. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655957/ https://www.ncbi.nlm.nih.gov/pubmed/34504311 http://dx.doi.org/10.1038/s41385-021-00440-4 |
Ejemplares similares
-
A Novel Supplementation Approach to Enhance Host Response to Sublingual Vaccination
por: Rowe, John C., et al.
Publicado: (2019) -
Neutrophils negatively regulate induction of mucosal IgA responses after sublingual immunization
por: Jee, Junbae, et al.
Publicado: (2015) -
IKKβ in intestinal epithelial cells regulates allergen-specific IgA and allergic inflammation at distant mucosal sites
por: Bonnegarde-Bernard, Astrid, et al.
Publicado: (2013) -
Routes of Allergic Sensitization and Myeloid Cell IKKβ Differentially Regulate Antibody Responses and Allergic Airway Inflammation in Male and Female Mice
por: Bonnegarde-Bernard, Astrid, et al.
Publicado: (2014) -
Insights Into Mucosal Innate Immune Responses in House Dust Mite-Mediated Allergic Asthma
por: Abu Khweek, Arwa, et al.
Publicado: (2020)