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Quantitative mechanistic model reveals key determinants of placental IgG transfer and informs prenatal immunization strategies

Transplacental antibody transfer is crucially important in shaping neonatal immunity. Recently, prenatal maternal immunization has been employed to boost pathogen-specific immunoglobulin G (IgG) transfer to the fetus. Multiple factors have been implicated in antibody transfer, but how these key regu...

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Detalles Bibliográficos
Autores principales: Wessel, Remziye E., Dolatshahi, Sepideh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656024/
https://www.ncbi.nlm.nih.gov/pubmed/37934786
http://dx.doi.org/10.1371/journal.pcbi.1011109