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The SMYD3-MAP3K2 signaling axis promotes tumor aggressiveness and metastasis in prostate cancer
Aberrant activation of Ras/Raf/mitogen-activated protein kinase (MAPK) signaling is frequently linked to metastatic prostate cancer (PCa); therefore, the characterization of modulators of this pathway is critical for defining therapeutic vulnerabilities for metastatic PCa. The lysine methyltransfera...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656069/ https://www.ncbi.nlm.nih.gov/pubmed/37976356 http://dx.doi.org/10.1126/sciadv.adi5921 |