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Concomitant use of magnesium oxide significantly decreases absorption of levodopa preparations in patients with Parkinson’s disease

INTRODUCTION: Constipation is one of the most frequent non-motor symptoms of Parkinson's disease (PD), and magnesium oxide (MgO) is a frequently used laxative. This study aimed to investigate the effect of concomitant use of MgO on the pharmacokinetics of levodopa preparations in patients with...

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Detalles Bibliográficos
Autores principales: Miyaue, Noriyuki, Yabe, Hayato, Nagai, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656210/
https://www.ncbi.nlm.nih.gov/pubmed/38021340
http://dx.doi.org/10.1016/j.prdoa.2023.100227