Reactive nitrogen species inhibit branched chain alpha-ketoacid dehydrogenase complex and impact muscle cell metabolism

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Branched chain α-ketoacid dehydrogenase complex (BCKDC) is the rate-limiting enzyme in branched chain amino acid (BCAA) catabolism, a metabolic pathway with great importance for human health. BCKDC belongs to the mitochondrial α-ketoacid dehydrogenase complex family, which also includes pyruvate deh...

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Detalles Bibliográficos
Autores principales: Arp, Nicholas L., Seim, Gretchen L., Votava, James A., Josephson, Jordyn, Fan, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656228/
https://www.ncbi.nlm.nih.gov/pubmed/37827290
http://dx.doi.org/10.1016/j.jbc.2023.105333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656228/
https://www.ncbi.nlm.nih.gov/pubmed/37827290
http://dx.doi.org/10.1016/j.jbc.2023.105333

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