High-speed AFM imaging reveals DNA capture and loop extrusion dynamics by cohesin-NIPBL

3D chromatin organization plays a critical role in regulating gene expression, DNA replication, recombination, and repair. While initially discovered for its role in sister chromatid cohesion, emerging evidence suggests that the cohesin complex (SMC1, SMC3, RAD21, and SA1/SA2), facilitated by NIPBL,...

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Detalles Bibliográficos
Autores principales: Kaur, Parminder, Lu, Xiaotong, Xu, Qi, Irvin, Elizabeth Marie, Pappas, Colette, Zhang, Hongshan, Finkelstein, Ilya J., Shi, Zhubing, Tao, Yizhi Jane, Yu, Hongtao, Wang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656236/
https://www.ncbi.nlm.nih.gov/pubmed/37774974
http://dx.doi.org/10.1016/j.jbc.2023.105296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656236/
https://www.ncbi.nlm.nih.gov/pubmed/37774974
http://dx.doi.org/10.1016/j.jbc.2023.105296

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