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High-speed AFM imaging reveals DNA capture and loop extrusion dynamics by cohesin-NIPBL
3D chromatin organization plays a critical role in regulating gene expression, DNA replication, recombination, and repair. While initially discovered for its role in sister chromatid cohesion, emerging evidence suggests that the cohesin complex (SMC1, SMC3, RAD21, and SA1/SA2), facilitated by NIPBL,...
Autores principales: | Kaur, Parminder, Lu, Xiaotong, Xu, Qi, Irvin, Elizabeth Marie, Pappas, Colette, Zhang, Hongshan, Finkelstein, Ilya J., Shi, Zhubing, Tao, Yizhi Jane, Yu, Hongtao, Wang, Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656236/ https://www.ncbi.nlm.nih.gov/pubmed/37774974 http://dx.doi.org/10.1016/j.jbc.2023.105296 |
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