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Nicotine plays a protective role in rats with induced viral pneumonia with polyinosinic-polycytidylic acid through α7nAChR

OBJECTIVE: To study the effect of nicotine in rat model of pneumonia induced by polyinosinic-polycytidylic acid [Poly (I:C)] and explore the underlying mechanism. METHODS: Twenty-four healthy adult male Sprague-Dawley (SD) rats (200–250 g) were randomly divided into normal saline control group (NS g...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Zhu, Yi, Yan, Hong, Ren, Lingyun, Chen, Jingli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656239/
https://www.ncbi.nlm.nih.gov/pubmed/38027680
http://dx.doi.org/10.1016/j.heliyon.2023.e21667