KLHL29-mediated DDX3X degradation promotes chemosensitivity by abrogating cell cycle checkpoint in triple-negative breast cancer

Triple-negative breast cancer (TNBC) is a heterogeneous breast cancer subtype and accounts for approximately 15–20% of breast cancer cases. In this study, we identified KLHL29, which is an understudied member of the Kelch-like gene family, as a crucial tumor suppressor that regulates chemosensitivit...

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Detalles Bibliográficos
Autores principales: Yao, Litong, Hao, Qian, Wang, Mozhi, Chen, Yuhai, Cao, Hongyi, Zhang, Qiang, Yu, Keda, Jiang, Yizhou, Shao, Zhiming, Zhou, Xiang, Xu, Yingying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656286/
https://www.ncbi.nlm.nih.gov/pubmed/37845393
http://dx.doi.org/10.1038/s41388-023-02858-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656286/
https://www.ncbi.nlm.nih.gov/pubmed/37845393
http://dx.doi.org/10.1038/s41388-023-02858-5

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