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KLHL29-mediated DDX3X degradation promotes chemosensitivity by abrogating cell cycle checkpoint in triple-negative breast cancer
Triple-negative breast cancer (TNBC) is a heterogeneous breast cancer subtype and accounts for approximately 15–20% of breast cancer cases. In this study, we identified KLHL29, which is an understudied member of the Kelch-like gene family, as a crucial tumor suppressor that regulates chemosensitivit...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656286/ https://www.ncbi.nlm.nih.gov/pubmed/37845393 http://dx.doi.org/10.1038/s41388-023-02858-5 |