Aloperine targets lysosomes to inhibit late autophagy and induces cell death through apoptosis and paraptosis in glioblastoma

Glioblastoma (GBM) is an aggressive intracranial tumour, and current chemotherapy regimens have limited efficacy. Aloperine (ALO), a natural alkaline compound, has shown potential as an antitumor agent. However, the effect of ALO against GBM remains unclear. This study aimed to investigate the funct...

Descripción completa

Detalles Bibliográficos
Autores principales: Tang, Ting, Liang, Hui, Wei, Wuting, Han, Yanling, Cao, Liang, Cong, Zixiang, Luo, Shiqiao, Wang, Handong, Zhou, Meng-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656413/
https://www.ncbi.nlm.nih.gov/pubmed/37975957
http://dx.doi.org/10.1186/s43556-023-00155-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656413/
https://www.ncbi.nlm.nih.gov/pubmed/37975957
http://dx.doi.org/10.1186/s43556-023-00155-x

Ejemplares similares