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Aloperine targets lysosomes to inhibit late autophagy and induces cell death through apoptosis and paraptosis in glioblastoma
Glioblastoma (GBM) is an aggressive intracranial tumour, and current chemotherapy regimens have limited efficacy. Aloperine (ALO), a natural alkaline compound, has shown potential as an antitumor agent. However, the effect of ALO against GBM remains unclear. This study aimed to investigate the funct...
Autores principales: | Tang, Ting, Liang, Hui, Wei, Wuting, Han, Yanling, Cao, Liang, Cong, Zixiang, Luo, Shiqiao, Wang, Handong, Zhou, Meng-Liang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656413/ https://www.ncbi.nlm.nih.gov/pubmed/37975957 http://dx.doi.org/10.1186/s43556-023-00155-x |
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