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Anti-inflammatory reprogramming of microglia cells by metabolic modulators to counteract neurodegeneration; a new role for Ranolazine

Microglia chronic activation is a hallmark of several neurodegenerative diseases, including the retinal ones, possibly contributing to their etiopathogenesis. However, some microglia sub-populations have anti-inflammatory and neuroprotective functions, thus making arduous deciphering the role of the...

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Detalles Bibliográficos
Autores principales: Piano, Ilaria, Votta, Arianna, Colucci, Patrizia, Corsi, Francesca, Vitolo, Sara, Cerri, Chiara, Puppi, Dario, Lai, Michele, Maya-Vetencourt, José Fernando, Leigheb, Massimiliano, Gabellini, Chiara, Ferraro, Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656419/
https://www.ncbi.nlm.nih.gov/pubmed/37978212
http://dx.doi.org/10.1038/s41598-023-47540-8