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Feedforward regulatory logic controls the specification-to-differentiation transition and terminal cell fate during Caenorhabditis elegans endoderm development

The architecture of gene regulatory networks determines the specificity and fidelity of developmental outcomes. We report that the core regulatory circuitry for endoderm development in Caenorhabditis elegans operates through a transcriptional cascade consisting of six sequentially expressed GATA-typ...

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Detalles Bibliográficos
Autores principales: Ewe, Chee Kiang, Sommermann, Erica M., Kenchel, Josh, Flowers, Sagen E., Maduro, Morris F., Joshi, Pradeep M., Rothman, Joel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656426/
https://www.ncbi.nlm.nih.gov/pubmed/35758255
http://dx.doi.org/10.1242/dev.200337