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Feedforward regulatory logic controls the specification-to-differentiation transition and terminal cell fate during Caenorhabditis elegans endoderm development
The architecture of gene regulatory networks determines the specificity and fidelity of developmental outcomes. We report that the core regulatory circuitry for endoderm development in Caenorhabditis elegans operates through a transcriptional cascade consisting of six sequentially expressed GATA-typ...
Autores principales: | Ewe, Chee Kiang, Sommermann, Erica M., Kenchel, Josh, Flowers, Sagen E., Maduro, Morris F., Joshi, Pradeep M., Rothman, Joel H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656426/ https://www.ncbi.nlm.nih.gov/pubmed/35758255 http://dx.doi.org/10.1242/dev.200337 |
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