Mechanistic insights into the alterations and regulation of the AKT signaling pathway in diabetic retinopathy

In the early stages of diabetic retinopathy (DR), diabetes-related hyperglycemia directly inhibits the AKT signaling pathway by increasing oxidative stress or inhibiting growth factor expression, which leads to retinal cell apoptosis, nerve proliferation and fundus microvascular disease. However, du...

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Detalles Bibliográficos
Autores principales: Li, Jiayuan, Chen, Kuangqi, Li, Xiang, Zhang, Xuhong, Zhang, Liyue, Yang, Qianjie, Xia, Yutong, Xie, Chen, Wang, Xiawei, Tong, Jianping, Shen, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656479/
https://www.ncbi.nlm.nih.gov/pubmed/37978169
http://dx.doi.org/10.1038/s41420-023-01717-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656479/
https://www.ncbi.nlm.nih.gov/pubmed/37978169
http://dx.doi.org/10.1038/s41420-023-01717-2

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