Inflammatory macrophages reprogram to immunosuppression by reducing mitochondrial translation

Acute inflammation can either resolve through immunosuppression or persist, leading to chronic inflammation. These transitions are driven by distinct molecular and metabolic reprogramming of immune cells. The anti-diabetic drug Metformin inhibits acute and chronic inflammation through mechanisms sti...

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Detalles Bibliográficos
Autores principales: Cortés, Marlies, Brischetto, Agnese, Martinez-Campanario, M. C., Ninfali, Chiara, Domínguez, Verónica, Fernández, Sara, Celis, Raquel, Esteve-Codina, Anna, Lozano, Juan J., Sidorova, Julia, Garrabou, Gloria, Siegert, Anna-Maria, Enrich, Carlos, Pintado, Belén, Morales-Ruiz, Manuel, Castro, Pedro, Cañete, Juan D., Postigo, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656499/
https://www.ncbi.nlm.nih.gov/pubmed/37978290
http://dx.doi.org/10.1038/s41467-023-42277-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656499/
https://www.ncbi.nlm.nih.gov/pubmed/37978290
http://dx.doi.org/10.1038/s41467-023-42277-4

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