Direct-acting antiviral resistance of Hepatitis C virus is promoted by epistasis

Direct-acting antiviral agents (DAAs) provide efficacious therapeutic treatments for chronic Hepatitis C virus (HCV) infection. However, emergence of drug resistance mutations (DRMs) can greatly affect treatment outcomes and impede virological cure. While multiple DRMs have been observed for all cur...

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Detalles Bibliográficos
Autores principales: Zhang, Hang, Quadeer, Ahmed Abdul, McKay, Matthew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656532/
https://www.ncbi.nlm.nih.gov/pubmed/37978179
http://dx.doi.org/10.1038/s41467-023-42550-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656532/
https://www.ncbi.nlm.nih.gov/pubmed/37978179
http://dx.doi.org/10.1038/s41467-023-42550-6

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