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Minimal residual disease detection by next-generation sequencing of different immunoglobulin gene rearrangements in pediatric B-ALL

While the prognostic role of immunoglobulin heavy chain locus (IGH) rearrangement in minimal residual disease (MRD) in pediatric B-acute lymphoblastic leukemia (B-ALL) has been reported, the contribution of light chain loci (IGK/IGL) remains elusive. This study is to evaluate the prognosis of IGH an...

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Detalles Bibliográficos
Autores principales: Chen, Haipin, Gu, Miner, Liang, Juan, Song, Hua, Zhang, Jingying, Xu, Weiqun, Zhao, Fenying, Shen, Diying, Shen, Heping, Liao, Chan, Tang, Yongmin, Xu, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656538/
https://www.ncbi.nlm.nih.gov/pubmed/37978187
http://dx.doi.org/10.1038/s41467-023-43171-9