Surveillance of SARS-CoV-2 immunogenicity: loss of immunodominant HLA-A*02-restricted epitopes that activate CD8(+) T cells

INTRODUCTION AND METHODS: In this present work, coronavirus subfamilies and SARS-CoV-2 Variants of Concern (VOCs) were investigated for the presence of MHC-I immunodominant viral peptides using in silico and in vitro tools. RESULTS: In our results, HLA-A*02 haplotype showed the highest number of imm...

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Detalles Bibliográficos
Autores principales: Lopes-Ribeiro, Ágata, Oliveira, Patrícia de Melo, Retes, Henrique Morais, Barbosa-Stancioli, Edel Figueiredo, da Fonseca, Flávio Guimarães, Tsuji, Moriya, Coelho-dos-Reis, Jordana Grazziela Alves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656734/
https://www.ncbi.nlm.nih.gov/pubmed/38022506
http://dx.doi.org/10.3389/fimmu.2023.1229712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656734/
https://www.ncbi.nlm.nih.gov/pubmed/38022506
http://dx.doi.org/10.3389/fimmu.2023.1229712

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