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The spike protein of SARS-CoV-2 induces inflammation and EMT of lung epithelial cells and fibroblasts through the upregulation of GADD45A

Lung epithelial cells and fibroblasts poorly express angiotensin-converting enzyme 2, and the study aimed to investigate the role of the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on inflammation and epithelial–mesenchymal transition (EMT) in two lung cell lines an...

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Detalles Bibliográficos
Autores principales: Cai, Jiehao, Ma, Wenjie, Wang, Xiangshi, Chang, Hailing, Wei, Zhongqiu, Li, Jingjing, Zeng, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656760/
https://www.ncbi.nlm.nih.gov/pubmed/38025528
http://dx.doi.org/10.1515/med-2023-0779