Loss of p53-DREAM-mediated repression of cell cycle genes as a driver of lymph node metastasis in head and neck cancer

BACKGROUND: The prognosis for patients with head and neck cancer (HNC) is poor and has improved little in recent decades, partially due to lack of therapeutic options. To identify effective therapeutic targets, we sought to identify molecular pathways that drive metastasis and HNC progression, throu...

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Detalles Bibliográficos
Autores principales: Brennan, Kevin, Espín-Pérez, Almudena, Chang, Serena, Bedi, Nikita, Saumyaa, Saumyaa, Shin, June Ho, Plevritis, Sylvia K., Gevaert, Olivier, Sunwoo, John B., Gentles, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656821/
https://www.ncbi.nlm.nih.gov/pubmed/37978395
http://dx.doi.org/10.1186/s13073-023-01236-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656821/
https://www.ncbi.nlm.nih.gov/pubmed/37978395
http://dx.doi.org/10.1186/s13073-023-01236-w

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