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In-silico study of antisense oligonucleotide antibiotics

BACKGROUND: The rapid emergence of antibiotic-resistant bacteria directly contributes to a wave of untreatable infections. The lack of new drug development is an important driver of this crisis. Most antibiotics today are small molecules that block vital processes in bacteria. To optimize such effec...

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Detalles Bibliográficos
Autores principales: Chen, Erica S., Ho, Eric S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10656905/
https://www.ncbi.nlm.nih.gov/pubmed/38025700
http://dx.doi.org/10.7717/peerj.16343