Cargando…

Fatty acids abrogate the growth-suppressive effects induced by inhibition of cholesterol flux in pancreatic cancer cells

BACKGROUND: Despite therapeutic advances, the prognosis of pancreatic ductal adenocarcinoma (PDAC) remains extremely poor. Metabolic reprogramming is increasingly recognized as a key contributor to tumor progression and therapy resistance in PDAC. One of the main metabolic changes essential for tumo...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Yuchuan, Amrutkar, Manoj, Finstadsveen, Anette Vefferstad, Dalen, Knut Tomas, Verbeke, Caroline S., Gladhaug, Ivar P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657020/
https://www.ncbi.nlm.nih.gov/pubmed/37978383
http://dx.doi.org/10.1186/s12935-023-03138-8