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The Impact of FGFR3 Alterations on the Tumor Microenvironment and the Efficacy of Immune Checkpoint Inhibitors in Bladder Cancer

BACKGROUND: Currently, only limited knowledge is available regarding the phenotypic association between fibroblast growth factor receptor 3 (FGFR3) alterations and the tumor microenvironment (TME) in bladder cancer (BLCA). METHODS: A multi-omics analysis on 389 BLCA and 35 adjacent normal tissues fr...

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Detalles Bibliográficos
Autores principales: Komura, Kazumasa, Hirosuna, Kensuke, Tokushige, Satoshi, Tsujino, Takuya, Nishimura, Kazuki, Ishida, Mitsuaki, Hayashi, Takuo, Ura, Ayako, Ohno, Takaya, Yamazaki, Shogo, Nakamori, Keita, Kinoshita, Shoko, Maenosono, Ryoichi, Ajiro, Masahiko, Yoshikawa, Yuki, Takai, Tomoaki, Tsutsumi, Takeshi, Taniguchi, Kohei, Tanaka, Tomohito, Takahara, Kiyoshi, Konuma, Tsuyoshi, Inamoto, Teruo, Hirose, Yoshinobu, Ono, Fumihito, Shiraishi, Yuichi, Yoshimi, Akihide, Azuma, Haruhito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10657138/
https://www.ncbi.nlm.nih.gov/pubmed/37980528
http://dx.doi.org/10.1186/s12943-023-01897-6